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00:00 - What is Allergic Bronchopulmonary Aspergillosis?
02:14 - Pathophysiology of Allergic Bronchopulmonary Aspergillosis
04:36 - Symptoms and Signs of Allergic Bronchopulmonary Aspergillosis
05:12 - Diagnosis of Allergic Bronchopulmonary Aspergillosis
08:31 - Treatment of Allergic Bronchopulmonary Aspergillosis
10:50 - Key Points
11:51 - Conclusion
Allergic bronchopulmonary aspergillosis is a hypersensitivity reaction to Aspergillus species (generally A. fumigatus) that occurs almost exclusively in patients with asthma or, less commonly, cystic fibrosis. Immune responses to Aspergillus antigens cause airway obstruction and, if untreated, bronchiectasis and pulmonary fibrosis. Symptoms and signs are those of asthma with the addition of productive cough and, occasionally, fever and anorexia. Diagnosis is suspected based on history and imaging tests and confirmed by Aspergillus skin testing and measurement of IgE levels, circulating precipitins, and A. fumigatus–specific antibodies. Treatment is with corticosteroids and, in patients with refractory disease, itraconazole.
#asthma
#aspergillosis
#lungsdisease
Professor Armen Astvatsatryan, MD, PhD, ScD, FESC. First Dean and Founder of Faculty of Public Health of European Regional Educational Academy (now University). One of 100 of the International Biographical Center`s (Cambridge, England) Top Health Professionals - 2007.
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