New Biosensor Tracks Single-Cell Molecular Changes in the Living Mouse Brain

For more information, see Laviv et al., Neuron, (19)31037-2. Laviv et al. established an experimental approach to visualize the spatiotemporal dynamics of CREB activity combined with calcium in single cells in the brain of living mice. This approach could be generalized to utilize various biosensors for a wide range of signaling molecules important for synaptic plasticity.