Which chromosome is associated with Huntington’s disease?

Huntington’s disease is associated with mutations on chromosome 4, where the HTT gene is located. This gene mutation involves the expansion of a CAG trinucleotide repeat, which leads to the production of an abnormal version of the huntingtin protein. The presence of this mutation on chromosome 4 is directly responsible for the development of Huntington’s disease, a hereditary neurodegenerative disorder. The length of the CAG repeat is inversely related to the age of onset of the disease symptoms, with a larger number of repeats leading to earlier onset. The identification of chromosome 4 as the site of the HTT gene mutation has been pivotal in understanding the genetic basis of Huntington’s disease, enabling genetic testing for at-risk individuals and research into potential therapies targeting the underlying genetic defect. Problem: Which chromosome is associated with Huntington’s disease? A) Chromosome 21 B) Chromosome 4 C) Chromosome 10 D) Chromosome X