Lower levels of vitamin D, higher rates of death
Association of Serum 25-Hydroxyvitamin D Concentrations With All-Cause and Cause-Specific Mortality Among Adult Patients With Existing Cardiovascular Disease
Observational study, non-interventional
Background
Vitamin D, lower levels, common in patients with cardiovascular disease (CVD)
Study of patients with existing CVD
Prospectively examine the associations of serum 25-hydroxyvitamin D [25(OH)D] concentrations with,
All-cause mortality and,
cause-specific mortality
Methods
N = 37,079 patients with CVD from the UK
Biobank study
From a prospective cohort of half a million, aged 40–69 years
CVD
Coronary heart disease
Atrial fibrillation
Heart failure
Stroke
Results
Among 37,079 patients with CVD at baseline, 57.5% were vitamin D deficient
Deficient, 25[OH]D less than 50 nmol/L (less than 20ng/ml)
Median follow-up of 11.7 years
Deaths that occurred = 6,319
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