The (European) Mandrake plant has been used since ancient times as a medicinal plant and has a tradition associated with magical activities. It is a member of the nightshade family. It contains hyoscyamine, scopolamine, and mandragorin. Medically, it has been used as a pain killer and a sedative. It was used in ancient times for surgery. An overdose, though, can be fatal. - Harry Potter Wiki
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