Wnt/β-Catenin Signaling Pathway | Overview, Purpose and APC Mutations

Lesson on the Wnt/β-Catenin signaling pathway (also known as simply the Wnt signaling pathway), including an introduction to the pathway, Wnt growth stimulatory factors, β-Catenin regulation and role of the pathway in growth, proliferation and development. Wnt proteins act as The Wnt signaling pathway is critically important in embryonic development, particularly in the development of the heart. As such the Wnt/β-Catenin signaling pathway is highly conserved. However, if mutations occur in proteins in the pathway, such as mutations in the adenomatous polyposis coli (APC) gene, this can lead to inappropriate activation of the Wnt/β-Catenin signaling pathway. NOTE: In the video, I misspoke and said that Beta catenin enters the “mitochondria“ - I meant to say it enters the nucleus. Sorry about the confusion everyone. Hope you find the video helpful :) Hey everyone, here is another biomedical lesson, and this one is on the canonical Wnt signaling pathway. In this less