X-linked refers to genes that are on the X chromosome. So the X chromosome is one of the two sex chromosomes that we have in humans. Females have two X chromosomes, and males have an X and a Y chromosome. Most genes on the X chromosome, when mutated, only show a phenotype in males. And that’s because, since females have two X chromosomes, the chromosome that doesn’t have a mutation can often compensate for the other X chromosome if it has a mutation. Some X-linked conditions that individuals may be familiar with are Fragile X syndrome, hemophilia A, and Duchenne muscular dystrophy. But there are some conditions that are more common in females, such as Rett syndrome, which is also due to mutation on the X chromosome.
#XChromosome #ChromosomeAwardWinningWork #probability #geneticDisorder #geneticDisease #ProductRule
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