[Andrew Huberman] Journal Club with Dr. Peter Attia | Effects of Light & Dark on Mental Health & Treatments for Cancer

🎯 Загружено автоматически через бота: 🚫 Оригинал видео: 📺 Данное видео является собственностью канала Andrew Huberman. Оно представлено в нашем сообществе исключительно в информационных, научных, образовательных или культурных целях. Наше сообщество не утверждает никаких прав на данное видео. Пожалуйста, поддержите автора, посетив его оригинальный канал: @hubermanlab. ✉️ Если у вас есть претензии к авторским правам на данное видео, пожалуйста, свяжитесь с нами по почте support@, и мы немедленно удалим его. 📃 Оригинальное описание: In this journal club episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins-trained physician focusing on healthspan and lifespan and the host of The Drive podcast. We each present a peer-reviewed scientific paper chosen because it contains novel, interesting, and actionable data. First, we discuss a paper on how bright light exposure at sunrise and throughout the day and dark exposure at night independently improve mental health and can offset some of the major symptoms of mental health disorders such as depression and anxiety. Then, we discuss an article that explores a novel class of immunotherapy treatments to combat cancer. We also discuss some of the new data on low-calorie sweeteners and if they are safe. This episode should be of interest to listeners curious about maximizing their vitality and longevity and to anyone seeking science-supported ways to improve mental health and lifespan. Thank you to our sponsors AG1: Eight Sleep: BetterHelp: Joovvv: LMNT: Momentous: Dr. Peter Attia Website: The Drive Podcast: Newsletter: Early Medical: X: Instagram: Facebook: YouTube: Journal Articles Day and night light exposure are associated with psychiatric disorders: an objective light study in greater than 85,000 people (first article discussed): Early evening light mitigates sleep compromising physiological and alerting responses to subsequent late evening light: Absence of Circadian Phase Resetting in Response to Bright Light Behind the Knees: Time spent in outdoor light is associated with mood, sleep, and circadian rhythm-related outcomes: A cross-sectional and longitudinal study in over 400,000 UK Biobank participants: Improved Survival with Ipilimumab in Patients with Metastatic Melanoma (second article discussed): Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation: Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer): Autoimmunity Correlates With Tumor Regression in Patients With Metastatic Melanoma Treated With Anti–Cytotoxic T-Lymphocyte Antigen-4: Other Resources Tuo: Light Meter app (Google Play): Light Meter app (App Store): Carbon app: Fluorescence & Mammals: Dr. Alia Crum: Science of Mindsets for Health & Performance: Sugar Substitutes: The mechanisms of action for immune checkpoint inhibitors: Timestamps 00:00:00 Dr. Peter Attia, Journal Club 00:02:40 Sponsors: Eight Sleep, BetterHelp & Joovv 00:07:14 Light, Dark & Mental Health; Retina 00:11:16 Outdoor vs. Indoor Light, Cataracts, Sunglasses 00:16:17 Tools: Sunrise & Sunsets, Circadian Rhythm; Midday Light 00:24:55 Tools: Night & Light Exposure; Waking Before Sunrise 00:31:05 Article #1, Light/Dark Exposure & Mental Health 00:36:50 Sponsor: AG1 00:38:18 Odds Ratio, Hazard Ratio 00:45:43 Night vs. Daylight Exposure, Mental Health Disorders 00:51:35 Major Depression & Light Exposure; Error Bars & Significance 00:59:15 Sponsor: LMNT 01:00:39 Prescriptions; Environmental & Artificial Light; Red Lights 01:08:14 Nighttime Light Exposure; Sleep Trackers & Belief Effects 01:13:54 Light Directionality, Phone, Night 01:17:21 Light Wavelengths & Sensors; Sunglasses 01:20:58 Hawthorne Effect, Reverse Causality, Genetics 01:26:26 Artificial Sweeteners, Appetite 01:31:16 Natural Light Cycles, Circadian Rhythm & Mental Health 01:39:53 Article #2, Immune System & Cancer 01:43:18 T-Cell Activation; Viruses 01:50:41 Autoimmunity; Cancer & Immune System Evasion 02:00:09 Checkpoint Inhibitors, CTLA-4 02:06:45 Anti-CTLA-4 Study Drug (Ipi