The World’s First Artificial Womb For Humans @ChildrensHospPhila
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The Biobag may not look much like a womb, but it contains the same key parts: a clear plastic bag that encloses the fetal lamb and protects it from the outside world, like the uterus would; an electrolyte solution that bathes the lamb similarly to the amniotic fluid in the uterus; and a way for the fetus to circulate its blood and exchange carbon dioxide for oxygen. Flake and his colleagues published their results today in the journal Nature Communications.
Flake hopes the Biobag will improve the care options for extremely premature infants, who have “well documented, dismal outcomes,” he says. Prematurity is the leading cause of death for newborns. In the US, about 10 percent of babies are born prematurely — which means they were born before they reach 37 weeks of pregnancy. About 6 percent, or 30,000 of those births, are considered extremely premature, which means that they were born at or before the 28th week of pregnancy.
These infants require intensive support as they continue to develop outside their mothers’ bodies. The babies who survive delivery require mechanical ventilation, medications, and IVs that provide nutrition and fluids. If they make it out of the intensive care unit, many of these infants (between 20 to 50 percent of them) still suffer from a host of health conditions that arise from the stunted development of their organ systems.
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